Wittenborn, T. R., Hagert, C. F., Ferapontov, A., Fonager, S., Jensen, L., Winther, G. & Degn, S. E. (2021).
Comparison of gamma and x-ray irradiation for myeloablation and establishment of normal and autoimmune syngeneic bone marrow chimeras.
PLoS One,
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https://doi.org/10.1371/journal.pone.0247501
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B cell MHC haplotype affects follicular inclusion, germinal center participation and plasma cell differentiation in a mouse model of lupus.
Frontiers in Immunology,
14, Article 1258046.
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The extrafollicular response is sufficient to drive initiation of autoimmunity and early disease hallmarks of lupus.
Frontiers in Immunology,
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Follicular Dendritic Cells Modulate Germinal Center B Cell Diversity through FcγRIIB.
Cell Reports,
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& Jensenius, J. C. (2009).
Polymorphisms in mannan-binding lectin (MBL)-associated serine protease 2 affect stability, binding to MBL, and enzymatic activity.
Journal of Immunology,
182(5), 2939-47.
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Mannan-binding lectin (MBL)-associated serine protease-1 (MASP-1), a serine protease associated with humoral pattern-recognition molecules: normal and acute-phase levels in serum and stoichiometry of lectin pathway components.
Clinical and Experimental Immunology. Supplement,
169(1), 38-48.
https://doi.org/10.1111/j.1365-2249.2012.04584.x
Sirinian, C., Papanastasiou, A. D.
, Degn, S. E., Frantzi, T., Aronis, C., Chaniotis, D., Makatsoris, T., Koutras, A. & Kalofonos, H. P. (2021).
Rank-c expression sensitizes er-negative, egfr-positive breast cancer cells to egfr-tyrosine kinase inhibitors (Tkis).
Genes,
12(11), Article 1686.
https://doi.org/10.3390/genes12111686Sirinian, C., Papanastasiou, A. D., Karayel, O.
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Analysis of RANK-c interaction partners identifies TRAF3 as a critical regulator of breast cancer aggressiveness.
NeoPlasia,
33, Article 100836.
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Multiparametric Optimization of Human Primary B-Cell Cultures Using Design of Experiments.
Scandinavian Journal of Immunology,
102(2), Article e70043.
https://doi.org/10.1111/sji.70043
Rasmussen, M. Q., Tindbæk, G., Nielsen, M. M., Merrild, C., Steiniche, T., Pedersen, J. S., Moestrup, S. K., Degn, S. E. & Madsen, M. (2023).
Epigenetic Silencing of LRP2 Is Associated with Dedifferentiation and Poor Survival in Multiple Solid Tumor Types.
Cancers,
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https://doi.org/10.3390/cancers15061830
Rasmussen, M. Q., Bønnelykke-Behrndtz, M. L., Merrild, C., Tvilling, I. K. S., Christensen, J. N., Nielsen, M. M., Georgsen, J. B., Naumann, N., Gudbergsson, J. M., Etzerodt, A., Pedersen, J. S., Jenkins, R. W.
, Degn, S. E., Moestrup, S. K., Schmidt, H., Steiniche, T. & Madsen, M. (2025).
LRP2 Expression in Melanoma Is Associated With a Transitory Cell State, Increased T Cell Infiltration, and Is Upregulated by IFNy Signaling.
Pigment Cell & Melanoma Research,
38(5), Article e70053.
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, Degn, S. E., Georgiou, P. & Mouzaki, A. (2018).
Clinical and immunological parameters of Sjögren's syndrome.
Autoimmunity Reviews,
17(10), 1053-1064.
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& Howard, K. A. (2025).
Exploiting FcRn engagement of an albumin-CpG oligonucleotide covalent conjugate for potent TLR9 immune induction.
Journal of Biological Chemistry,
301(6), Article 108508.
https://doi.org/10.1016/j.jbc.2025.108508
Pedersen, K., Green, K., Kristoffersen, E. L., Schinkel, T., Hansen, A. G., Palarasah, Y.
, Rovsing, A. B., Andersen, E. S., Valero, J., Civit, L., Laursen, N. S., Troldborg, A., Degn, S. E. & Thiel, S. (2026).
Curbing Autoimmunity: A New Fab Fragment Targeting CD40-CD40L Halts B-Cell Activation and Differentiation.
European Journal of Immunology,
56(2), Article e70158.
https://doi.org/10.1002/eji.70158
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& Mikkelsen, J. G. (2024).
Cell-targeted gene modification by delivery of CRISPR-Cas9 ribonucleoprotein complexes in pseudotyped lentivirus-derived nanoparticles.
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Endogenous Natural Complement Inhibitor Regulates Cardiac Development.
Journal of Immunology,
198(8), 3118-3126.
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Morsing, A. E.
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Age-associated B cells enhance tertiary lymphoid structures in the liver and promote HCC formation.
Hepatology Communications,
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Characterization of DNA-protein complexes by nanoparticle tracking analysis and their association with systemic lupus erythematosus.
Proceedings of the National Academy of Sciences (PNAS),
118(30), Article e2106647118.
https://doi.org/10.1073/pnas.2106647118
Joseph, J. V., Blaavand, M. S., Cai, H., Vernejoul, F.
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STING activation counters glioblastoma by vascular alteration and immune surveillance.
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B Cell Intrinsic STING Signaling Is Not Required for Autoreactive Germinal Center Participation.
Frontiers in Immunology,
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Gonzalez, S. F.
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Trafficking of B cell antigen in lymph nodes.
Annual Review of Immunology,
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, Degn, S. E., Turley, S. J. & Carroll, M. C. (2010).
Complement-dependent transport of antigen into B cell follicles.
Journal of Immunology,
185, 2659-2664.
Gonzalez, S. F., Lukacs-Kornek, V., Kuligowski, M. P., Pitcher, L. A.
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Capture of influenza by medullary dendritic cells via SIGN-R1 is essential for humoral immunity in draining lymph nodes.
Nature Immunology,
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Increased maternofoetal transfer of antibodies in a murine model of systemic lupus erythematosus, but no immune activation and neuroimmune sequelae in offspring.
Journal of Neuroimmunology,
370, Article 577927.
https://doi.org/10.1016/j.jneuroim.2022.577927
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, Luo, Y., Lin, L. & Degn, S. E. (2025).
Maternal imprinting of autoreactivity in a murine model of systemic lupus erythematosus.
Brain, Behavior, and Immunity,
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https://doi.org/10.1016/j.bbi.2025.07.025
Ferapontov, A., Omer, M., Baudrexel, I.
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Antigen footprint governs activation of the B cell receptor.
Nature Communications,
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Fahlquist-Hagert, C., Wittenborn, T. R., Terczyńska-Dyla, E., Kastberg, K. S., Yang, E., Rallistan, A. N., Markett, Q. R.
, Winther, G., Fonager, S., Voss, L. F., Pedersen, M. K.
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Antigen presentation by B cells enables epitope spreading across an MHC barrier.
Nature Communications,
14(1), Article 6941.
https://doi.org/10.1038/s41467-023-42541-7
Fahlquist-Hagert, C., Wittenborn, T. R., Pedersen, M. K.
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T-follicular regulatory cells expand to control germinal center plasma cell output but fail to curb autoreactivity.
iScience,
27(10), Article 110887.
https://doi.org/10.1016/j.isci.2024.110887
Fahlquist-Hagert, C., Wittenborn, T. R., Ferapontov, A., Jensen, L., Terczyńska-Dyla, E. & Degn, S. E. (2024).
Haplosufficiency of MHCII in autoreactive germinal center B cells.
European Journal of Immunology,
54(1), Article 2350422.
https://doi.org/10.1002/eji.202350422
Degn, S. E., Hansen, A., Steffensen, R., Jacobsen, C., Jensenius, J. C. & Thiel, S. (2009).
MAp44, a human protein associated with pattern recognition molecules of the complement system and regulating the lectin pathway of complement activation.
Journal of Immunology,
183(11), 7371-8.
https://doi.org/10.4049/jimmunol.0902388
Degn, S. E., Jensen, L., Gál, P., Dobó, J., Holmvad, S. H.
, Jensenius, J. C. & Thiel, S. (2010).
Biological variations of MASP-3 and MAp44, two splice products of the MASP1 gene involved in regulation of the complement system.
Journal of Immunological Methods,
361(1-2), 37-50.
https://doi.org/10.1016/j.jim.2010.07.006
Degn, S. E., Thiel, S., Nielsen, O.
, Hansen, A. G., Steffensen, R. & Jensenius, J. C. (2011).
MAp19, the alternative splice product of the MASP2 gene.
Journal of Immunological Methods,
373(1-2), 89-101.
https://doi.org/10.1016/j.jim.2011.08.006
Degn, S. E., Andersen, S. H., Jensen, L., Thiel, S. & Jensenius, J. C. (2011).
Assay interference caused by antibodies reacting with rat kappa light-chain in human sera.
Journal of Immunological Methods,
372(1-2), 204-8.
https://doi.org/10.1016/j.jim.2011.06.030
Degn, S. E., Jensen, L., Hansen, A. G., Duman, D., Tekin, M.
, Jensenius, J. C. & Thiel, S. (2012).
Mannan-Binding Lectin-Associated Serine Protease (MASP)-1 Is Crucial for Lectin Pathway Activation in Human Serum, whereas neither MASP-1 nor MASP-3 Is Required for Alternative Pathway Function.
Journal of Immunology,
189(8), 3957-69.
https://doi.org/10.4049/jimmunol.1201736
Degn, S. E., Jensen, L., Olszowski, T.
, Jensenius, J. C. & Thiel, S. (2013).
Co-complexes of MASP-1 and MASP-2 associated with the soluble pattern-recognition molecules drive lectin pathway activation in a manner inhibitable by MAp44.
Journal of Immunology,
191(3), 1334-45.
https://doi.org/10.4049/jimmunol.1300780
Degn, S. E., Kjaer, T. R., Kidmose, R. T., Jensen, L., Hansen, A. G., Tekin, M.
, Jensenius, J. C., Andersen, G. R. & Thiel, S. (2014).
Complement activation by ligand-driven juxtaposition of discrete pattern recognition complexes.
Proceedings of the National Academy of Sciences (PNAS),
111(37), 13445-13450.
https://doi.org/10.1073/pnas.1406849111
Degn, S. E., van der Poel, C. E., Firl, D. J., Ayoglu, B., Al Qureshah, F. A., Bajic, G., Mesin, L., Reynaud, C.-A., Weill, J.-C., Utz, P. J., Victora, G. D. & Carroll, M. C. (2017).
Clonal Evolution of Autoreactive Germinal Centers.
Cell,
170(5), 913-926.
https://doi.org/10.1016/j.cell.2017.07.026